HitPredict

Interactor 1: BRX1 (Q8TDN6)
Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2)
Gene: BRIX1

Interactor 2: RL36 (Q9Y3U8)
Large ribosomal subunit protein eL36 (60S ribosomal protein L36)
Gene: RPL36

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Brix~Ribosomal_L36e
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 353 Hs			1 105
+	Hs
		1291784 IMP4_HUMAN (2-272): 6.92e-91: 275: 17.56		RL36_HUMAN (1-105): 4.02e-34: 115: 100.00
+	Hs
		1334506 RPF1_HUMAN (13-269): 1.37e-72: 230: 20.83		RL36_HUMAN (1-105): 4.02e-34: 115: 100.00
+	Sc
		406130 RPF1_YEAST (4-269): 5.6e-62: 201: 15.33		RL36A_YEAST (1-99): 4.39e-28: 99.7: 46.47
+	Hs
		1332939 RPF2_HUMAN (106-247): 1.01e-31: 122: 22.88		RL36_HUMAN (1-105): 4.02e-34: 115: 100.00
+	Hs
		1343176 SSF1_HUMAN (54-228): 2.87e-21: 96.4: 15.22		RL36_HUMAN (1-105): 4.02e-34: 115: 100.00
+	Sc
		145716 RPF2_YEAST (71-267): 1.62e-13: 72.5: 19.56		RL36B_YEAST (1-99): 1.11e-28: 101: 47.48
+	Sc
		406122 RPF2_YEAST (71-267): 1.62e-13: 72.5: 19.56		RL36A_YEAST (1-99): 4.39e-28: 99.7: 46.47