Interactor 1: NEK7 (Q8TDX7)
Serine/threonine-protein kinase Nek7 (EC 2.7.11.34) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)
Gene: NEK7

Interactor 2: NEK6 (Q9HC98)
Serine/threonine-protein kinase Nek6 (EC 2.7.11.34) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512)
Gene: NEK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 26186194, 28514442, 17353931, 33961781, 32707033, 32814053
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, validated two hybrid, two hybrid array, two hybrid pooling approach, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000922 - spindle pole
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 302
Hs

1 313
+ Hs
+ At
+ At
+ At
+ At
+ At
+ Hs
+ Hs
+ At
+ At
+ Hs
+ Mm
+ Zm
+ At
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024