HitPredict

Interactor 1: ES8L1 (Q8TE68)
Epidermal growth factor receptor kinase substrate 8-like protein 1 (EPS8-like protein 1) (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-related protein 1)
Gene: EPS8L1

Interactor 2: NUD12 (Q9BQG2)
NAD-capped RNA hydrolase NUDT12 (DeNADding enzyme NUDT12) (EC 3.6.1.-) (NADH pyrophosphatase NUDT12) (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12)
Gene: NUDT12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 723 Hs			1 462
+	Hs
		166918 EPS8_HUMAN (3-716): 0: 754: 34.96		ANR28_HUMAN (2-143): 2.35e-20: 96.4: 17.93
+	Hs
		411885 LCK_HUMAN (417-701): 3.51e-67: 232: 15.36		KDIS_HUMAN (2-259): 2.16e-28: 121: 11.63
+	Hs
		434072 LYN_HUMAN (451-704): 2.54e-55: 199: 15.89		ANR50_HUMAN (2-174): 2.97e-30: 126: 19.65
+	Hs
		434071 LYN_HUMAN (451-704): 2.54e-55: 199: 15.89		KDIS_HUMAN (2-259): 2.16e-28: 121: 11.63
+	Hs
		411697 LCK_HUMAN (417-701): 3.51e-67: 232: 15.36		ANK3_HUMAN (280-459): 6.6e-16: 82.9: 12.90
+	Hs
		433701 LYN_HUMAN (451-704): 2.54e-55: 199: 15.89		ANK2_HUMAN (162-454): 4.34e-25: 111: 9.38
+	Hs
		411845 LCK_HUMAN (417-701): 3.51e-67: 232: 15.36		TANC1_HUMAN (2-235): 1.5e-12: 72.1: 14.09
+	Hs
		412433 FYN_HUMAN (430-704): 9.77e-56: 201: 13.07		MYO16_HUMAN (10-220): 2.85e-18: 90.2: 13.68
+	Hs
		433730 LYN_HUMAN (451-704): 2.54e-55: 199: 15.89		ANK3_HUMAN (280-459): 6.6e-16: 82.9: 12.90
+	Hs
		433991 LYN_HUMAN (451-704): 2.54e-55: 199: 15.89		TANC1_HUMAN (2-235): 1.5e-12: 72.1: 14.09
+	Hs
		208966 NCK2_HUMAN (478-605): 1.59e-36: 143: 23.70		PSD10_HUMAN (20-233): 8.66e-23: 98.3: 16.74
+	Hs
		557660 NCK1_HUMAN (478-605): 5.2e-32: 130: 22.96		ANK2_HUMAN (162-454): 4.34e-25: 111: 9.38
+	Hs
		209098 NCK2_HUMAN (478-605): 1.59e-36: 143: 23.70		ANS1B_HUMAN (83-388): 8.08e-18: 88.7: 10.71
+	Hs
		209067 NCK2_HUMAN (478-605): 1.59e-36: 143: 23.70		ANR55_HUMAN (3-193): 3.29e-13: 73.7: 20.49
+	Hs
		209048 NCK2_HUMAN (478-605): 1.59e-36: 143: 23.70		ILK_HUMAN (9-100): 3.03e-11: 67.1: 28.26
+	Hs
		557772 NCK1_HUMAN (478-605): 5.2e-32: 130: 22.96		EHMT2_HUMAN (6-100): 1.28e-09: 62.9: 23.16