HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: TNIP2 (Q8NFZ5)
TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein)
Gene: TNIP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27609421
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 429
+	Hs
		1245132 ITCH_HUMAN (1-870): 0: 902: 54.26		TNIP2_HUMAN (1-429): 0: 648: 100.00
+	Hs
		1245178 WWP1_HUMAN (1-870): 0: 888: 58.38		TNIP2_HUMAN (1-429): 0: 648: 100.00
+	Hs
		1245192 SMUF1_HUMAN (1-385): 1.35e-45: 177: 17.77		TNIP2_HUMAN (1-429): 0: 648: 100.00