HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: RBM14 (Q96PK6)
RNA-binding protein 14 (Paraspeckle protein 2) (PSP2) (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein)
Gene: RBM14

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25071155, 31048545
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 669
+	Hs
		1294836 ITCH_HUMAN (1-870): 0: 902: 54.26		RBM14_HUMAN (1-669): 4.16e-69: 239: 100.00
+	Hs
		1299361 WWP1_HUMAN (1-870): 0: 888: 58.38		RBM14_HUMAN (1-669): 4.16e-69: 239: 100.00
+	Hs
		125122 WWP2_HUMAN (1-870): 0: 982: 100.00		PABP1_HUMAN (3-538): 5.24e-33: 137: 13.49
+	Hs
		125430 WWP2_HUMAN (1-870): 0: 982: 100.00		PABP4_HUMAN (71-151): 5.98e-10: 64.2: 23.60
+	Hs
		516643 ITCH_HUMAN (1-870): 0: 902: 54.26		PABP1_HUMAN (3-538): 5.24e-33: 137: 13.49
+	Hs
		808233 NEDD4_HUMAN (90-867): 0: 731: 35.94		RBM14_HUMAN (1-669): 4.16e-69: 239: 100.00
+	Hs
		1192197 HUWE1_HUMAN (241-869): 7.77e-179: 575: 30.03		RBM4_HUMAN (1-349): 9.22e-63: 214: 27.22
+	Hs
		1299376 SMUF2_HUMAN (1-363): 5.89e-43: 169: 17.62		RBM14_HUMAN (1-669): 4.16e-69: 239: 100.00