Interactor 1: SMCR8 (Q8TEV9)
Guanine nucleotide exchange protein SMCR8 (Smith-Magenis syndrome chromosomal region candidate gene 8 protein)
Gene: SMCR8
Interactor 2: CI072 (Q96LT7)
Guanine nucleotide exchange factor C9orf72
Gene: C9orf72
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.977 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30669939, 27617292, 27103069, 27107012, 32296183, 33961781, unassigned1304, 29950492 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, validated two hybrid, barcode fusion genetics two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C9orf72-like~Folliculin |
| Common GO terms | GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005737 - cytoplasm GO:0006914 - autophagy GO:0010506 - regulation of autophagy GO:0032045 - guanyl-nucleotide exchange factor complex and 6 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
