HitPredict

Interactor 1: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Interactor 2: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0032266 - phosphatidylinositol-3-phosphate binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1356 Hs			1 1116
+	Hs
		1153304 PARD3_HUMAN (1-1356): 0: 709: 100.00		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Hs
		1136433 PARD3_HUMAN (1-1356): 0: 709: 100.00		MAGI3_HUMAN (1-1116): 3.96e-94: 331: 9.76
+	Hs
		1256924 PARD3_HUMAN (1-1356): 0: 709: 100.00		PKHA6_HUMAN (109-1116): 8.74e-73: 264: 28.52
+	Hs
		1256866 PARD3_HUMAN (1-1356): 0: 709: 100.00		MAGI1_HUMAN (1-1111): 1.6e-43: 175: 9.66
+	Hs
		1256895 PARD3_HUMAN (1-1356): 0: 709: 100.00		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43
+	Hs
		1256890 PARD3_HUMAN (1-1356): 0: 709: 100.00		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1256852 PARD3_HUMAN (1-1356): 0: 709: 100.00		TITIN_HUMAN (275-1090): 3.45e-10: 67: 9.15
+	Hs
		1153341 MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Ce
		86408 C1P635_CAEEL (117-743): 5.12e-65: 242: 16.95		G5EE23_CAEEL (131-787): 1.4e-67: 248: 12.82
+	Mm
		1143518 DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98		MAGI3_MOUSE (1-1115): 3e-83: 299: 9.62
+	Ce
		103468 DLG1_CAEEL (165-827): 8.04e-62: 232: 16.79		TTN1_CAEEL (273-1105): 1.48e-42: 173: 10.84
+	Dm
		1001633 Q0KHR3_DROME (42-1082): 6.25e-62: 235: 20.76		Q9W2L2_DROME (4-633): 7.38e-42: 169: 11.16
+	Ce
		86389 C1P633_CAEEL (438-686): 2.36e-31: 136: 21.85		G5EE23_CAEEL (131-787): 1.4e-67: 248: 12.82
+	Mm
		1194486 DLG2_MOUSE (192-784): 2.75e-43: 173: 14.69		CNKR2_MOUSE (120-329): 2.5e-47: 186: 26.94
+	Hs
		1199788 MAGI2_HUMAN (68-1181): 1.8e-38: 159: 13.66		MAGI1_HUMAN (1-1111): 1.6e-43: 175: 9.66
+	Ce
		88173 D3YT29_CAEEL (438-686): 2.81e-30: 131: 21.85		G5EG76_CAEEL (17-814): 1e-40: 165: 12.62
+	Mm
		1143379 DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98		CNKR2_MOUSE (120-329): 2.5e-47: 186: 26.94
+	Mm
		1194481 DLG1_MOUSE (274-579): 3.13e-22: 106: 17.50		CNKR2_MOUSE (120-329): 2.5e-47: 186: 26.94
+	Rn
		677809 DLG4_RAT (540-699): 1e-22: 107: 27.98		CNKR2_RAT (120-329): 4.34e-47: 185: 26.48
+	Hs
		280075 MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43