HitPredict

Interactor 1: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Interactor 2: RHOF (Q9HBH0)
Rho-related GTP-binding protein RhoF (Rho family GTPase Rif) (Rho in filopodia)
Gene: RHOF

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1356 Hs			1 211
+	Hs
		120555 PARD3_HUMAN (1-1356): 0: 709: 100.00		RHOD_HUMAN (5-198): 4.14e-90: 265: 52.06
+	Hs
		925463 PARD3_HUMAN (1-1356): 0: 709: 100.00		RAC1_HUMAN (20-211): 9.06e-84: 248: 49.48
+	Hs
		545520 PARD3_HUMAN (1-1356): 0: 709: 100.00		RAC2_HUMAN (20-211): 2.82e-79: 237: 49.48
+	Hs
		951182 PARD3_HUMAN (1-1356): 0: 709: 100.00		RHOG_HUMAN (19-211): 4.47e-79: 236: 46.11
+	Hs
		900726 PARD3_HUMAN (1-1356): 0: 709: 100.00		RHOA_HUMAN (21-211): 1.51e-78: 235: 48.69
+	Hs
		564626 PARD3_HUMAN (1-1356): 0: 709: 100.00		RHOQ_HUMAN (14-209): 4.28e-77: 232: 46.43
+	Hs
		892503 PARD3_HUMAN (1-1356): 0: 709: 100.00		RAC3_HUMAN (20-193): 1.33e-77: 232: 50.58
+	Hs
		894244 PARD3_HUMAN (1-1356): 0: 709: 100.00		CDC42_HUMAN (19-211): 1.19e-77: 232: 44.04
+	Hs
		436425 PARD3_HUMAN (1-1356): 0: 709: 100.00		RHOC_HUMAN (21-211): 1.44e-76: 230: 49.22
+	Hs
		915860 PARD3_HUMAN (1-1356): 0: 709: 100.00		RHOB_HUMAN (21-200): 2.02e-58: 184: 48.89
+	Hs
		900727 PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37		RHOA_HUMAN (21-211): 1.51e-78: 235: 48.69
+	Hs
		436426 PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37		RHOC_HUMAN (21-211): 1.44e-76: 230: 49.22
+	Hs
		915861 PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37		RHOB_HUMAN (21-200): 2.02e-58: 184: 48.89
+	Dm
		776949 X2JFU8_DROME (1-1082): 9.49e-78: 285: 21.87		CDC42_DROME (19-211): 5.08e-77: 231: 44.04
+	Hs
		120710 NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36		RHOD_HUMAN (5-198): 4.14e-90: 265: 52.06
+	Hs
		545697 NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36		RAC2_HUMAN (20-211): 2.82e-79: 237: 49.48
+	Hs
		564735 NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36		RHOQ_HUMAN (14-209): 4.28e-77: 232: 46.43
+	Hs
		892678 NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36		RAC3_HUMAN (20-193): 1.33e-77: 232: 50.58
+	Hs
		894581 NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36		CDC42_HUMAN (19-211): 1.19e-77: 232: 44.04
+	Hs
		436569 NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36		RHOC_HUMAN (21-211): 1.44e-76: 230: 49.22