HitPredict

Interactor 1: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	24255178
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008104 - protein localization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1356 Hs			1 1088
+	Hs
		325825 PARD3_HUMAN (1-1356): 0: 709: 100.00		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		568742 PARD3_HUMAN (1-1356): 0: 709: 100.00		KAPCA_HUMAN (635-1024): 1.31e-133: 410: 31.73
+	Hs
		1232910 LNX2_HUMAN (50-361): 6.83e-21: 101: 11.35		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		280078 MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1137888 PARD3_HUMAN (1-1356): 0: 709: 100.00		MRCKA_HUMAN (656-1007): 6.11e-76: 277: 41.23
+	Hs
		325772 MAGI3_HUMAN (61-1272): 3.28e-32: 139: 10.65		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		280011 MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Dm
		1001628 Q0KHR3_DROME (42-1082): 6.25e-62: 235: 20.76		WARTS_DROME (167-1039): 7.21e-137: 443: 39.71
+	Hs
		1073454 PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Ce
		88187 D3YT29_CAEEL (438-686): 2.81e-30: 131: 21.85		WARTS_CAEEL (393-1050): 8.43e-135: 432: 35.98
+	Hs
		1073495 PZRN3_HUMAN (126-1085): 4.45e-67: 249: 13.26		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Mm
		554913 DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98		KPCE_MOUSE (554-1010): 2.84e-130: 415: 29.92
+	Mm
		933108 DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98		KAPCB_MOUSE (638-1022): 3.87e-133: 409: 31.62
+	Hs
		1073494 NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		1073444 MAGI2_HUMAN (68-1181): 1.8e-38: 159: 13.66		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		1073434 MAGI3_HUMAN (61-1272): 3.28e-32: 139: 10.65		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		1073438 PZRN4_HUMAN (450-1168): 4.41e-29: 128: 13.00		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Mm
		1143553 DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98		KS6A2_MOUSE (519-973): 2.65e-79: 277: 19.79
+	Hs
		942348 DLG4_HUMAN (540-699): 1.03e-22: 107: 27.98		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Mm
		936586 DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98		ROCK2_MOUSE (640-1008): 1.72e-66: 247: 37.17