HitPredict

Interactor 1: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Interactor 2: AMOL2 (Q9Y2J4)
Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP)
Gene: AMOTL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24255178
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1356 Hs			1 779
+	Hs
		1119005 PARD3_HUMAN (1-1356): 0: 709: 100.00		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1222250 PARD3_HUMAN (1-1356): 0: 709: 100.00		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		1137888 PARD3_HUMAN (1-1356): 0: 709: 100.00		MRCKA_HUMAN (242-732): 6.78e-18: 91.3: 12.33
+	Hs
		280045 MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		280087 MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		1020172 PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1119035 MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1300698 MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		1118998 INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1199783 MAGI2_HUMAN (68-1181): 1.8e-38: 159: 13.66		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		1350451 NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36		CING_HUMAN (175-776): 2.05e-17: 89.3: 9.97
+	Mm
		1225208 MPDZ_MOUSE (452-543): 1.11e-20: 101: 42.39		AMOL2_MOUSE (1-779): 2.27e-58: 214: 86.17
+	Hs
		280051 MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Mm
		1257405 MPDZ_MOUSE (452-543): 1.11e-20: 101: 42.39		AMOT_MOUSE (1-661): 2.13e-38: 156: 38.02
+	Mm
		1257408 MPDZ_MOUSE (452-543): 1.11e-20: 101: 42.39		AMOL1_MOUSE (1-761): 1.46e-38: 156: 38.96
+	Hs
		1222264 MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Mm
		1145448 PTN13_MOUSE (265-1002): 1.38e-17: 91.5: 16.56		AMOT_MOUSE (1-661): 2.13e-38: 156: 38.02
+	Mm
		936586 DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98		ROCK2_MOUSE (307-661): 3.25e-12: 72.4: 17.02
+	Hs
		1020232 PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50		CING_HUMAN (175-776): 2.05e-17: 89.3: 9.97
+	Hs
		1300684 MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16		CING_HUMAN (175-776): 2.05e-17: 89.3: 9.97