Interactor 1: MRE11 (Q8U1N9)
DNA double-strand break repair protein Mre11 (EC 3.1.-.-) (pfMre11)
Gene: MRE11

Interactor 2: MRE11 (Q8U1N9)
DNA double-strand break repair protein Mre11 (EC 3.1.-.-) (pfMre11)
Gene: MRE11

Species: Pyrococcus furiosus DSM 3638

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 18854158, 21458667
Identification Methods molecular sieving, x ray scattering, cross-linking study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~Metallophos
Common GO terms GO:0000403 - Y-form DNA binding
GO:0000729 - DNA double-strand break processing
GO:0004519 - endonuclease activity
GO:0004520 - DNA endonuclease activity
GO:0004529 - DNA exonuclease activity
and 4 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 426
Pf

1 426
+ Mm
+ Hs
+ Sc
+ Sp
+ Mj
+ Tm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024