HitPredict

Interactor 1: FBXW7 (Q8VBV4)
F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10)
Gene: FBXW7

Interactor 2: SKP1 (Q9WTX5)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1)
Gene: SKP1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 25670854, 29472293, 11735228, 23955342
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box-like~Skp1
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019005 - SCF ubiquitin ligase complex
GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 710
Mm

1 163
+ Hs
+ Dm
+ Sp
+ Sc
+ Sp
+ Hs
+ Hs
+ Sp
+ Ce
+ Sc
+ Sp
+ Hs
+ Hs
+ Ce
+ Mm
+ Xl
+ Dm
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024