Interactor 1: MAVS (Q8VCF0)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Interactor 2: ASC (Q9EPB4)
Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein)
Gene: Pycard

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 25847972
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002218 - activation of innate immune response
GO:0002230 - positive regulation of defense response to virus by host
GO:0005739 - mitochondrion
GO:0032755 - positive regulation of interleukin-6 production
GO:0032760 - positive regulation of tumor necrosis factor production
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 503
Mm

1 193
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024