HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31048545
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 197
+	Hs
		125592 WWP2_HUMAN (1-870): 0: 982: 100.00		INADL_HUMAN (112-194): 6.16e-11: 62.8: 30.12
+	Hs
		1252467 WWP1_HUMAN (1-870): 0: 888: 58.38		LNX1_HUMAN (14-179): 1.21e-17: 82.1: 22.02
+	Hs
		1246432 WWP1_HUMAN (1-870): 0: 888: 58.38		INADL_HUMAN (112-194): 6.16e-11: 62.8: 30.12
+	Mm
		1143429 NED4L_MOUSE (4-867): 0: 781: 31.91		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		1271021 NED4L_HUMAN (5-867): 0: 785: 32.17		DLG3_HUMAN (74-164): 2.8e-20: 89.8: 35.42
+	Hs
		1299602 NED4L_HUMAN (5-867): 0: 785: 32.17		MAGI1_HUMAN (94-172): 5.41e-10: 60.1: 35.44
+	Mm
		93273 E9PXB7_MOUSE (151-867): 0: 684: 37.10		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Mm
		93267 E9PXB7_MOUSE (151-867): 0: 684: 37.10		DLG3_MOUSE (60-164): 3.31e-21: 92.5: 32.73
+	Hs
		1021523 HUWE1_HUMAN (241-869): 7.77e-179: 575: 30.03		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		1223645 HACE1_HUMAN (374-864): 5.08e-160: 492: 31.05		SNTG2_HUMAN (28-188): 1.75e-32: 124: 25.77
+	Mm
		808344 NEDD4_MOUSE (14-364): 2.31e-51: 196: 19.16		DLG3_MOUSE (60-164): 3.31e-21: 92.5: 32.73