HitPredict - High confidence protein-protein interactions

Interactor 1: MYCD (Q8VIM5)
Myocardin (Basic SAP coiled-coil transcription activator 2) (SRF cofactor protein)
Gene: Myocd

Interactor 2: SRF (Q9JM73)
Serum response factor (SRF)
Gene: SRF

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	11439182, 17360478
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0001666 - response to hypoxia GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 11 others more... GO:0006366 - transcription by RNA polymerase II GO:0007507 - heart development GO:0042826 - histone deacetylase binding GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0045987 - positive regulation of smooth muscle contraction GO:0060379 - cardiac muscle cell myoblast differentiation GO:0060947 - cardiac vascular smooth muscle cell differentiation GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:1900222 - negative regulation of amyloid-beta clearance GO:1902895 - positive regulation of miRNA transcription
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	935
Mm

1	504

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Last updated: 15 Jul 2024