HitPredict

Interactor 1: CDC7 (O00311)
Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)
Gene: CDC7

Interactor 2: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36398662
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 574 Hs			1 736
+	Hs
		150913 GSK3B_HUMAN (9-376): 3.67e-74: 244: 16.67		DVL2_HUMAN (1-736): 0: 547: 100.00
+	Hs
		150910 KC1E_HUMAN (50-396): 1.34e-53: 189: 17.63		DVL2_HUMAN (1-736): 0: 547: 100.00
+	Hs
		150905 KC1D_HUMAN (50-221): 2.7e-53: 188: 24.44		DVL2_HUMAN (1-736): 0: 547: 100.00
+	Hs
		150707 KS6A2_HUMAN (2-328): 3.35e-71: 244: 13.62		DVL1_HUMAN (11-736): 7.51e-163: 488: 57.32
+	Hs
		150904 KC1A_HUMAN (54-221): 1.31e-44: 163: 22.86		DVL2_HUMAN (1-736): 0: 547: 100.00
+	Hs
		151086 KC1AL_HUMAN (54-218): 5.87e-44: 161: 24.42		DVL2_HUMAN (1-736): 0: 547: 100.00
+	Hs
		150688 KC1E_HUMAN (50-396): 1.34e-53: 189: 17.63		DVL1_HUMAN (11-736): 7.51e-163: 488: 57.32
+	Hs
		150685 KC1D_HUMAN (50-221): 2.7e-53: 188: 24.44		DVL1_HUMAN (11-736): 7.51e-163: 488: 57.32
+	Hs
		830441 KC1E_HUMAN (50-396): 1.34e-53: 189: 17.63		DVL3_HUMAN (11-736): 4.58e-160: 482: 65.04
+	Hs
		822339 KC1D_HUMAN (50-221): 2.7e-53: 188: 24.44		DVL3_HUMAN (11-736): 4.58e-160: 482: 65.04
+	Mm
		1143553 KS6A2_MOUSE (2-311): 1.94e-86: 285: 13.42		DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85
+	Hs
		942348 KS6A1_HUMAN (2-310): 3.38e-83: 276: 13.76		DLG4_HUMAN (108-707): 2.94e-75: 259: 15.53
+	Hs
		1021498 KS6A2_HUMAN (2-328): 3.35e-71: 244: 13.62		DLG1_HUMAN (94-707): 5.4e-83: 284: 15.92
+	Hs
		1073494 KS6A1_HUMAN (2-310): 3.38e-83: 276: 13.76		NEB1_HUMAN (93-347): 2.94e-43: 171: 17.58
+	Hs
		1073434 KS6A1_HUMAN (2-310): 3.38e-83: 276: 13.76		MAGI3_HUMAN (223-577): 5.73e-16: 84.5: 11.78
+	Hs
		883917 KS6A1_HUMAN (2-310): 3.38e-83: 276: 13.76		SYJ2B_HUMAN (258-341): 2.66e-16: 78.4: 30.68
+	Hs
		1236912 KC1AL_HUMAN (54-218): 5.87e-44: 161: 24.42		NEB1_HUMAN (93-347): 2.94e-43: 171: 17.58
+	Hs
		835708 GSK3B_HUMAN (9-376): 3.67e-74: 244: 16.67		PTN13_HUMAN (97-531): 5.7e-17: 88: 15.40
+	Hs
		280037 GSK3B_HUMAN (9-376): 3.67e-74: 244: 16.67		MPDZ_HUMAN (242-350): 1.97e-12: 73.4: 28.18
+	Rn
		193535 KS6B1_RAT (360-558): 1.48e-11: 69.1: 13.94		NEB1_RAT (93-347): 2.47e-43: 171: 16.86