Interactor 1: CDC7 (O00311)
Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)
Gene: CDC7

Interactor 2: CDK4 (P11802)
Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)
Gene: CDK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 15232106
Identification Methods pull down, protein array
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 5 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 574
Hs

1 303
+ Hs
+ Hs
+ Sc
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+ Hs
+ At
+ At
+ Sp
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ At
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+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024