Interactor 1: CDC7 (O00311)
Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)
Gene: CDC7

Interactor 2: MCM4 (P33991)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21)
Gene: MCM4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 12614612, 22540012, 10846177
Identification Methods two hybrid, enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 574
Hs

1 863
+ Xl
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Sp
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024