HitPredict

Interactor 1: CSN3 (Q8W575)
COP9 signalosome complex subunit 3 (Signalosome subunit 3) (Protein FUSCA 11)
Gene: CSN3

Interactor 2: CSN7 (Q94JU3)
COP9 signalosome complex subunit 7 (CSN complex subunit 7) (Protein FUSCA 5)
Gene: CSN7

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.840

Property	Details
Experiments	11742986, 12615944, 15703063
Identification Methods	two hybrid, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	PCI~PCI
Common GO terms	GO:0000338 - protein deneddylation GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome GO:0009585 - red, far-red light phototransduction
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 429 At			1 260
+	Hs
		1334410 CSN3_HUMAN (6-428): 3.09e-116: 347: 37.76		CSN7B_HUMAN (1-255): 1.99e-79: 241: 32.56
+	Hs
		1354429 CSN3_HUMAN (6-428): 3.09e-116: 347: 37.76		CSN7A_HUMAN (12-255): 1.4e-75: 232: 30.28
+	At
		1278364 PSD11_ARATH (8-385): 8.2e-90: 280: 12.66		CSN7_ARATH (1-260): 4.96e-98: 288: 100.00
+	Dm
		1249185 CSN3_DROME (6-428): 4.16e-102: 312: 31.39		CSN7_DROME (2-257): 6.25e-81: 246: 32.56
+	Dm
		627127 PSMD3_DROME (8-420): 9.69e-100: 308: 19.72		Q7KMP8_DROME (24-191): 1.43e-51: 174: 20.23
+	Hs
		198755 PSMD3_HUMAN (47-424): 2.86e-96: 300: 20.51		PSD13_HUMAN (16-191): 1.36e-54: 181: 17.20
+	Hs
		897312 CSN2_HUMAN (33-384): 4.6e-73: 237: 11.17		CSN7B_HUMAN (1-255): 1.99e-79: 241: 32.56
+	Dm
		1277031 CSN2_DROME (36-384): 4.86e-68: 224: 12.09		CSN7_DROME (2-257): 6.25e-81: 246: 32.56
+	Hs
		897324 CSN2_HUMAN (33-384): 4.6e-73: 237: 11.17		CSN7A_HUMAN (12-255): 1.4e-75: 232: 30.28
+	Mm
		897342 CSN2_MOUSE (33-384): 4.6e-73: 237: 11.17		CSN7A_MOUSE (12-255): 1.71e-74: 229: 30.28
+	Hs
		121872 PSD11_HUMAN (55-393): 6.12e-81: 257: 13.19		PSD13_HUMAN (16-191): 1.36e-54: 181: 17.20
+	Dm
		1180705 PSD11_DROME (55-394): 6.36e-79: 252: 13.16		Q7KMP8_DROME (24-191): 1.43e-51: 174: 20.23
+	Sc
		766884 RPN3_YEAST (49-418): 1.79e-76: 248: 16.54		RPN9_YEAST (11-191): 1.48e-46: 161: 15.18
+	Dm
		1358197 CSN4_DROME (72-396): 5.67e-44: 159: 11.44		CSN7_DROME (2-257): 6.25e-81: 246: 32.56
+	Ce
		136315 CSN2_CAEEL (30-366): 1.13e-71: 235: 12.46		EIF3M_CAEEL (2-216): 1.3e-44: 156: 19.73
+	An
		961357 CSN2_EMENI (37-374): 8.1e-70: 230: 12.43		CSN7_EMENI (1-221): 8.33e-44: 152: 30.00
+	Sc
		978512 RPN6_YEAST (51-386): 1.27e-62: 210: 12.11		RPN9_YEAST (11-191): 1.48e-46: 161: 15.18