Interactor 1: CDC7 (O00311)
Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)
Gene: CDC7
Interactor 2: DBF4A (Q9UBU7)
Protein DBF4 homolog A (Activator of S phase kinase) (Chiffon homolog A) (DBF4-type zinc finger-containing protein 1)
Gene: DBF4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.988 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 32296183, 10523313, 33961781, 10373557, 17276990, 16912045, 10846177, 22540012, 30392930, 12614612, 32707033, 23064647, 31515488, unassigned1304, 16899510 |
| Identification Methods | affinity chromatography technology, two hybrid, enzymatic study, pull down, molecular sieving, x-ray crystallography, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~zf-DBF |
| Common GO terms | GO:0000082 - G1/S transition of mitotic cell cycle GO:0005654 - nucleoplasm GO:0010571 - positive regulation of nuclear cell cycle DNA replication |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
