Interactor 1: ABHD5 (Q8WTS1)
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) (Lipid droplet-binding protein CGI-58)
Gene: ABHD5

Interactor 2: PLPL2 (Q96AD5)
Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Calcium-independent phospholipase A2-zeta) (iPLA2-zeta) (EC 3.1.1.4) (Desnutrin) (Pigment epithelium-derived factor receptor) (PEDF-R) (TTS2.2) (Transport-secretion protein 2) (TTS2)
Gene: PNPLA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.633

The method score is based on:

Property Details
Experiments 17189257, 23297223
Identification Methods fluorescent resonance energy transfer, protein complementation assay, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005811 - lipid droplet
GO:0005829 - cytosol
GO:0010891 - negative regulation of sequestering of triglyceride
GO:0010898 - positive regulation of triglyceride catabolic process
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 349
Hs

1 504
+ Mm
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024