HitPredict

Interactor 1: UPK1A (O00322)
Uroplakin-1a (UP1a) (Tetraspanin-21) (Tspan-21) (Uroplakin Ia) (UPIa) (UPKa)
Gene: UPK1A

Interactor 2: S10A7 (P31151)
Protein S100-A7 (Psoriasin) (S100 calcium-binding protein A7)
Gene: S100A7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 258 Hs			1 101
+	Hs
		209338 TSN6_HUMAN (8-258): 1.94e-57: 185: 15.94		S1A7A_HUMAN (1-101): 8.52e-32: 108: 94.06
+	Hs
		209316 TSN6_HUMAN (8-258): 1.94e-57: 185: 15.94		S10A7_HUMAN (1-101): 8.48e-31: 106: 100.00
+	Hs
		209305 TSN6_HUMAN (8-258): 1.94e-57: 185: 15.94		S10A9_HUMAN (4-101): 4.09e-28: 99: 23.53
+	Hs
		887761 CD81_HUMAN (10-258): 8.78e-52: 170: 15.81		S10AA_HUMAN (2-90): 1.26e-31: 108: 23.60
+	Hs
		678430 CD81_HUMAN (10-258): 8.78e-52: 170: 15.81		S10A7_HUMAN (1-101): 8.48e-31: 106: 100.00
+	Hs
		209348 TSN6_HUMAN (8-258): 1.94e-57: 185: 15.94		S10AG_HUMAN (4-98): 1.78e-23: 88: 26.26
+	Hs
		209304 TSN6_HUMAN (8-258): 1.94e-57: 185: 15.94		S10A8_HUMAN (2-94): 6.39e-23: 86.1: 22.92
+	Hs
		125975 UPK1A_HUMAN (24-258): 1.11e-50: 168: 100.00		S10A2_HUMAN (1-92): 3.45e-28: 99.6: 22.11
+	Hs
		125958 UPK1A_HUMAN (24-258): 1.11e-50: 168: 100.00		S10A9_HUMAN (4-101): 4.09e-28: 99: 23.53
+	Hs
		416599 CD81_HUMAN (10-258): 8.78e-52: 170: 15.81		S10A6_HUMAN (2-92): 4.58e-23: 86.5: 23.40
+	Hs
		125957 UPK1A_HUMAN (24-258): 1.11e-50: 168: 100.00		S10A8_HUMAN (2-94): 6.39e-23: 86.1: 22.92