HitPredict

Interactor 1: RAB2B (Q8WUD1)
Ras-related protein Rab-2B (EC 3.6.5.2)
Gene: RAB2B

Interactor 2: RAB18 (Q9NP72)
Ras-related protein Rab-18
Gene: RAB18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005789 - endoplasmic reticulum membrane GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane and 1 others more... GO:0016192 - vesicle-mediated transport
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 206
+	Hs
		1273009 RAB8B_HUMAN (2-198): 1.07e-96: 281: 45.18		RAB1B_HUMAN (1-200): 8.72e-82: 243: 42.57
+	Mm
		877189 RAB8B_MOUSE (2-198): 3.07e-97: 283: 45.69		RAB8A_MOUSE (1-206): 6.2e-78: 233: 39.42
+	Hs
		894787 RAB8B_HUMAN (2-198): 1.07e-96: 281: 45.18		RAB8A_HUMAN (1-206): 1.3e-78: 235: 38.94
+	Hs
		918916 RAB2B_HUMAN (1-216): 1.82e-92: 271: 100.00		RAB1A_HUMAN (1-200): 1.22e-82: 245: 43.84
+	Hs
		1259991 RAB2B_HUMAN (1-216): 1.82e-92: 271: 100.00		RAB1B_HUMAN (1-200): 8.72e-82: 243: 42.57
+	Hs
		845875 RAB8B_HUMAN (2-198): 1.07e-96: 281: 45.18		RAB13_HUMAN (1-205): 1.44e-77: 232: 38.35
+	Zm
		73944 B4FAE1_MAIZE (3-216): 1.52e-86: 256: 45.79		B4FAE1_MAIZE (1-200): 2.43e-86: 255: 42.16
+	Zm
		75506 B4FJ62_MAIZE (1-216): 1.06e-90: 267: 45.41		B4FJ62_MAIZE (1-201): 3.08e-78: 235: 37.74
+	Hs
		895026 RAB2A_HUMAN (1-216): 2.31e-86: 256: 82.87		RAB1A_HUMAN (1-200): 1.22e-82: 245: 43.84
+	Hs
		895264 RAB2A_HUMAN (1-216): 2.31e-86: 256: 82.87		RAB1B_HUMAN (1-200): 8.72e-82: 243: 42.57
+	Dm
		185461 RAB2_DROME (1-216): 7.46e-88: 259: 83.33		O18332_DROME (2-199): 2.61e-78: 234: 41.58
+	Mm
		919000 RAB1A_MOUSE (3-216): 9.52e-84: 249: 43.93		RAB1B_MOUSE (1-200): 1.49e-81: 242: 42.08
+	Hs
		895216 RAB2A_HUMAN (1-216): 2.31e-86: 256: 82.87		RAB1C_HUMAN (1-200): 4e-78: 234: 40.59
+	Hs
		894715 RAB1A_HUMAN (3-216): 9.52e-84: 249: 43.93		RAB8A_HUMAN (1-206): 1.3e-78: 235: 38.94
+	Hs
		895217 RAB8B_HUMAN (2-198): 1.07e-96: 281: 45.18		RAB2A_HUMAN (9-187): 5.36e-55: 175: 50.00
+	Hs
		895204 RAB2B_HUMAN (1-216): 1.82e-92: 271: 100.00		RAB2A_HUMAN (9-187): 5.36e-55: 175: 50.00
+	Mm
		867146 RAB2B_MOUSE (1-216): 1.01e-89: 264: 94.91		RAB2A_MOUSE (9-187): 5.19e-55: 176: 50.00