HitPredict

Interactor 1: IASPP (Q8WUF5)
RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein)
Gene: PPP1R13L

Interactor 2: IASPP (Q8WUF5)
RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein)
Gene: PPP1R13L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.792

The method score is based on:

Property Details
Experiments 18275817, 23623661
Identification Methods isothermal titration calorimetry, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Ank_2, Ank_2~SH3_9, SH3_9~SH3_9
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003215 - cardiac right ventricle morphogenesis
GO:0003229 - ventricular cardiac muscle tissue development
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
and 14 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 828
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024