HitPredict

Interactor 1: HDAC7 (Q8WUI4)
Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a) (Protein deacetylase HDAC7) (EC 3.5.1.-)
Gene: HDAC7

Interactor 2: IKZF4 (Q9H2S9)
Zinc finger protein Eos (Ikaros family zinc finger protein 4)
Gene: IKZF4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12015313
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 952 Hs			1 585
+	Hs
		1033686 HDAC7_HUMAN (1-952): 0: 1051: 100.00		IKZF1_HUMAN (70-583): 7.61e-165: 481: 50.87
+	Hs
		1260200 HDAC7_HUMAN (1-952): 0: 1051: 100.00		IKZF3_HUMAN (61-583): 1.11e-144: 429: 43.02
+	Hs
		880822 HDAC4_HUMAN (20-939): 0: 958: 48.44		IKZF4_HUMAN (1-585): 1.35e-169: 496: 100.00
+	Hs
		880848 HDAC4_HUMAN (20-939): 0: 958: 48.44		IKZF2_HUMAN (66-582): 5.82e-168: 489: 56.11
+	Hs
		880715 HDAC4_HUMAN (20-939): 0: 958: 48.44		IKZF1_HUMAN (70-583): 7.61e-165: 481: 50.87
+	Hs
		880849 HDAC4_HUMAN (20-939): 0: 958: 48.44		IKZF3_HUMAN (61-583): 1.11e-144: 429: 43.02
+	Hs
		1329659 HDAC5_HUMAN (20-950): 0: 850: 41.21		IKZF4_HUMAN (1-585): 1.35e-169: 496: 100.00
+	Hs
		1356565 HDAC5_HUMAN (20-950): 0: 850: 41.21		IKZF2_HUMAN (66-582): 5.82e-168: 489: 56.11
+	Hs
		1033762 HDAC5_HUMAN (20-950): 0: 850: 41.21		IKZF1_HUMAN (70-583): 7.61e-165: 481: 50.87
+	Hs
		1356578 HDAC5_HUMAN (20-950): 0: 850: 41.21		IKZF3_HUMAN (61-583): 1.11e-144: 429: 43.02
+	Hs
		1038804 HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91		IKZF2_HUMAN (66-582): 5.82e-168: 489: 56.11
+	Hs
		1270436 HDAC2_HUMAN (513-948): 3.43e-167: 499: 20.71		IKZF4_HUMAN (1-585): 1.35e-169: 496: 100.00
+	Hs
		1033633 HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91		IKZF1_HUMAN (70-583): 7.61e-165: 481: 50.87
+	Hs
		1270517 HDAC2_HUMAN (513-948): 3.43e-167: 499: 20.71		IKZF2_HUMAN (66-582): 5.82e-168: 489: 56.11
+	Hs
		1033690 HDAC2_HUMAN (513-948): 3.43e-167: 499: 20.71		IKZF1_HUMAN (70-583): 7.61e-165: 481: 50.87
+	Hs
		1038805 HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91		IKZF3_HUMAN (61-583): 1.11e-144: 429: 43.02
+	Mm
		140300 HDAC1_MOUSE (510-916): 5.08e-171: 508: 21.91		Q8C5P6_MOUSE (81-277): 1.27e-73: 238: 64.47
+	Hs
		1038377 HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91		ZN273_HUMAN (102-276): 3.58e-52: 189: 28.73
+	Hs
		1158943 HDAC2_HUMAN (513-948): 3.43e-167: 499: 20.71		ZFP1_HUMAN (214-371): 1.61e-13: 74.8: 12.50
+	Hs
		1038742 HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91		PRDM5_HUMAN (161-266): 3.11e-09: 61.6: 29.25