HitPredict

Interactor 1: HDAC7 (Q8WUI4)
Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a) (Protein deacetylase HDAC7) (EC 3.5.1.-)
Gene: HDAC7

Interactor 2: TTF2 (Q9UNY4)
Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2)
Gene: TTF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 952 Hs			1 1162
+	Mm
		59025 HDAC4_MOUSE (20-940): 0: 938: 47.68		CHD6_MOUSE (101-1160): 0: 605: 15.14
+	Mm
		1000158 HDAC4_MOUSE (20-940): 0: 938: 47.68		CHD8_MOUSE (93-1160): 8.36e-180: 586: 15.51
+	Hs
		847111 HDAC9_HUMAN (20-892): 0: 869: 43.28		SMCA4_HUMAN (113-1159): 0: 593: 17.27
+	Mm
		56897 HDAC1_MOUSE (510-916): 5.08e-171: 508: 21.91		CHD5_MOUSE (114-1160): 0: 622: 15.50
+	Hs
		1038563 HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91		CHD5_HUMAN (114-1160): 0: 614: 15.32
+	Hs
		1018465 HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91		CHD3_HUMAN (170-1160): 0: 613: 15.72
+	Hs
		1018617 HDAC2_HUMAN (513-948): 3.43e-167: 499: 20.71		CHD3_HUMAN (170-1160): 0: 613: 15.72
+	Mm
		140261 HDAC1_MOUSE (510-916): 5.08e-171: 508: 21.91		SMCA4_MOUSE (113-1159): 0: 593: 17.18
+	Hs
		846962 HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91		SMCA4_HUMAN (113-1159): 0: 593: 17.27
+	Hs
		847037 HDAC2_HUMAN (513-948): 3.43e-167: 499: 20.71		SMCA4_HUMAN (113-1159): 0: 593: 17.27
+	Hs
		1038730 HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91		CHD8_HUMAN (93-1160): 2.85e-177: 579: 15.22
+	Dm
		332806 HDAC1_DROME (512-948): 4.66e-170: 507: 20.22		CHDM_DROME (53-1160): 2.73e-179: 578: 16.06
+	Hs
		1038382 HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91		CHD4_HUMAN (172-1160): 3.82e-178: 573: 15.46
+	Mm
		140286 HDAC1_MOUSE (510-916): 5.08e-171: 508: 21.91		CHD4_MOUSE (172-1160): 1.9e-177: 571: 15.46
+	Hs
		1059770 HDAC2_HUMAN (513-948): 3.43e-167: 499: 20.71		CHD4_HUMAN (172-1160): 3.82e-178: 573: 15.46
+	Hs
		846768 HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91		SMCA2_HUMAN (117-1159): 1.87e-177: 565: 16.00
+	Hs
		846833 HDAC2_HUMAN (513-948): 3.43e-167: 499: 20.71		SMCA2_HUMAN (117-1159): 1.87e-177: 565: 16.00
+	Dm
		1097627 HDAC1_DROME (512-948): 4.66e-170: 507: 20.22		ISWI_DROME (450-1158): 2.07e-174: 542: 19.40
+	Hs
		1038748 HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91		HELLS_HUMAN (378-1160): 8.61e-176: 540: 18.30
+	Hs
		229453 HDAC2_HUMAN (513-948): 3.43e-167: 499: 20.71		SMCA5_HUMAN (452-1162): 1.14e-175: 546: 20.03