Interactor 1: PDC6I (Q8WUM4)
Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95)
Gene: PDCD6IP

Interactor 2: CHM4A (Q9BY43)
Charged multivesicular body protein 4a (Chromatin-modifying protein 4a) (CHMP4a) (SNF7 homolog associated with Alix-2) (SNF7-1) (hSnf-1) (Vacuolar protein sorting-associated protein 32-1) (Vps32-1) (hVps32-1)
Gene: CHMP4A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.733

The method score is based on:

Property Details
Experiments 14505570, 21191027, 14505569, 18641129, 18511562, 17350572
Identification Methods two hybrid, affinity chromatography technology, x-ray crystallography, surface plasmon resonance, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0015031 - protein transport
GO:0016236 - macroautophagy
GO:0036258 - multivesicular body assembly
GO:0039702 - viral budding via host ESCRT complex
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 868
Hs

1 222
+ Hs
+ Hs
+ Dm
+ Hs
+ At
+ At
+ Dm
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024