HitPredict

Interactor 1: DEP1B (Q8WUY9)
DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8)
Gene: DEPDC1B

Interactor 2: RHBT2 (Q9BYZ6)
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)
Gene: RHOBTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 529 Hs			1 727
+	Hs
		297650 DEP1B_HUMAN (1-529): 0: 559: 100.00		RHBT1_HUMAN (1-708): 6.34e-160: 480: 67.65
+	Hs
		894255 DEP1B_HUMAN (1-529): 0: 559: 100.00		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Hs
		564629 DEP1B_HUMAN (1-529): 0: 559: 100.00		RHOQ_HUMAN (10-225): 1.24e-84: 267: 36.53
+	Hs
		545526 DEP1B_HUMAN (1-529): 0: 559: 100.00		RAC2_HUMAN (12-219): 9.54e-73: 236: 36.97
+	Hs
		892511 DEP1B_HUMAN (1-529): 0: 559: 100.00		RAC3_HUMAN (12-208): 3.69e-72: 234: 39.50
+	Hs
		925474 DEP1B_HUMAN (1-529): 0: 559: 100.00		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		951188 DEP1B_HUMAN (1-529): 0: 559: 100.00		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19
+	Hs
		900738 DEP1B_HUMAN (1-529): 0: 559: 100.00		RHOA_HUMAN (16-216): 1.94e-70: 230: 35.29
+	Hs
		914247 DEP1B_HUMAN (1-529): 0: 559: 100.00		RB11A_HUMAN (5-252): 2.31e-70: 230: 16.34
+	Mm
		892729 RHG33_MOUSE (173-520): 7.87e-68: 239: 16.30		CDC42_MOUSE (12-218): 7.09e-92: 286: 36.67
+	Hs
		894126 RHG17_HUMAN (39-508): 4.13e-64: 226: 15.06		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Mm
		892730 RHG32_MOUSE (173-497): 1.14e-61: 221: 14.54		CDC42_MOUSE (12-218): 7.09e-92: 286: 36.67
+	Dm
		776930 RHGF_DROME (51-517): 3.9e-81: 275: 12.58		RAC1_DROME (12-220): 1.37e-69: 227: 35.38
+	Hs
		64652 RHG32_HUMAN (173-497): 2.77e-61: 220: 14.54		RHOQ_HUMAN (10-225): 1.24e-84: 267: 36.53
+	Hs
		147862 RHG33_HUMAN (173-520): 5.6e-71: 248: 16.02		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		214294 RHG17_HUMAN (39-508): 4.13e-64: 226: 15.06		SPOP_HUMAN (305-670): 2.13e-72: 241: 13.30
+	Hs
		925329 RHG15_HUMAN (126-393): 3.82e-69: 231: 13.50		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		925354 RHG17_HUMAN (39-508): 4.13e-64: 226: 15.06		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		64649 RHG32_HUMAN (173-497): 2.77e-61: 220: 14.54		RAC2_HUMAN (12-219): 9.54e-73: 236: 36.97
+	Mm
		925803 RHG32_MOUSE (173-497): 1.14e-61: 221: 14.54		RAC1_MOUSE (12-220): 1.16e-71: 233: 35.38