HitPredict

Interactor 1: TM171 (Q8WVE6)
Transmembrane protein 171
Gene: TMEM171

Interactor 2: NED4L (Q96PU5)
E3 ubiquitin-protein ligase NEDD4-like (EC 2.3.2.26) (EC 2.3.2.36) (HECT-type E3 ubiquitin transferase NED4L) (NEDD4.2) (Nedd4-2)
Gene: NEDD4L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 324 Hs			1 975
+	Hs
		1261330 TM171_HUMAN (1-324): 0: 669: 100.00		ITCH_HUMAN (9-972): 0: 772: 33.16
+	Hs
		808204 TM171_HUMAN (1-324): 0: 669: 100.00		NEDD4_HUMAN (94-975): 0: 724: 49.78
+	Hs
		1261346 TM171_HUMAN (1-324): 0: 669: 100.00		HECW2_HUMAN (200-564): 1.39e-10: 67.7: 12.84
+	Hs
		1176341 TM171_HUMAN (1-324): 0: 669: 100.00		HECW1_HUMAN (144-528): 1.92e-09: 64.2: 13.73