HitPredict

Interactor 1: KBTB7 (Q8WVZ9)
Kelch repeat and BTB domain-containing protein 7
Gene: KBTBD7

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.909

Property	Details
Experiments	25684205, 16169070, 21900206, 20562859
Identification Methods	affinity chromatography technology, pull down, unspecified method, two hybrid, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	ATG8~KBTB_W-LIR
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 684 Hs			1 125
+	Hs
		891243 KBTB7_HUMAN (1-684): 3.49e-171: 507: 100.00		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306250 KBTB7_HUMAN (1-684): 3.49e-171: 507: 100.00		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1262059 KBTB7_HUMAN (1-684): 3.49e-171: 507: 100.00		MLP3C_HUMAN (1-120): 2.08e-51: 161: 55.00
+	Hs
		1262066 KBTB7_HUMAN (1-684): 3.49e-171: 507: 100.00		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		1201302 KBTB6_HUMAN (1-674): 7.18e-160: 478: 89.76		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		891206 KBTB6_HUMAN (1-674): 7.18e-160: 478: 89.76		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306221 KBTB6_HUMAN (1-674): 7.18e-160: 478: 89.76		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1201299 KBTB6_HUMAN (1-674): 7.18e-160: 478: 89.76		MLP3C_HUMAN (1-120): 2.08e-51: 161: 55.00
+	Hs
		1201303 KBTB6_HUMAN (1-674): 7.18e-160: 478: 89.76		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		1049322 KEAP1_HUMAN (433-682): 2.89e-47: 178: 16.79		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1049329 KEAP1_HUMAN (433-682): 2.89e-47: 178: 16.79		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		891139 KEAP1_HUMAN (433-682): 2.89e-47: 178: 16.79		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306167 KEAP1_HUMAN (433-682): 2.89e-47: 178: 16.79		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1049326 KEAP1_HUMAN (433-682): 2.89e-47: 178: 16.79		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		1299556 KLHL5_HUMAN (237-483): 3.89e-26: 116: 15.14		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		891272 KLHL5_HUMAN (237-483): 3.89e-26: 116: 15.14		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Dm
		1181841 Q7KSF5_DROME (283-482): 2.08e-25: 114: 12.44		Q9W2S2_DROME (7-122): 5.18e-54: 166: 31.03
+	Hs
		1120811 KLH12_HUMAN (505-684): 3.93e-20: 96.5: 12.11		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1120814 KLH12_HUMAN (505-684): 3.93e-20: 96.5: 12.11		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50