Interactor 1: ODPX (O00330)
Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX)
Gene: PDHX

Interactor 2: ODPA (P08559)
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I)
Gene: PDHA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 34079125
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 2-oxoacid_dh~E1_dh
Common GO terms GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006086 - acetyl-CoA biosynthetic process from pyruvate
GO:0045254 - pyruvate dehydrogenase complex
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 501
Hs

1 390
+ Hs
+ At
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs
+ Ce
+ Bs
+ Hs
+ At

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Last updated: 15 Jul 2024