HitPredict

Interactor 1: ODPX (O00330)
Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX)
Gene: PDHX

Interactor 2: IF2M (P46199)
Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt))
Gene: MTIF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 501 Hs			1 727
+	Hs
		505946 ODB2_HUMAN (1-500): 2.22e-155: 452: 24.56		IF2M_HUMAN (1-727): 0: 646: 100.00
+	Hs
		739021 ODO2_HUMAN (19-500): 2.29e-128: 382: 22.93		IF2M_HUMAN (1-727): 0: 646: 100.00
+	Hs
		126232 ODPX_HUMAN (1-501): 0: 586: 100.00		EFTU_HUMAN (172-419): 7.3e-68: 232: 25.35
+	Hs
		489717 ODP2_HUMAN (11-277): 8.66e-33: 134: 21.50		IF2M_HUMAN (1-727): 0: 646: 100.00
+	Hs
		505948 ODB2_HUMAN (1-500): 2.22e-155: 452: 24.56		EFTU_HUMAN (172-419): 7.3e-68: 232: 25.35
+	Sc
		367522 ODP2_YEAST (26-500): 3.04e-143: 421: 30.91		EFTU_YEAST (177-457): 1.62e-75: 252: 22.93
+	Hs
		739030 ODO2_HUMAN (19-500): 2.29e-128: 382: 22.93		EFTU_HUMAN (172-419): 7.3e-68: 232: 25.35
+	Hs
		489720 ODP2_HUMAN (11-277): 8.66e-33: 134: 21.50		EFTU_HUMAN (172-419): 7.3e-68: 232: 25.35
+	Ec
		420942 ODP2_ECOLI (58-132): 4.9e-11: 67.1: 29.33		SELB_ECOLI (182-406): 1.24e-12: 73.2: 29.83