Interactor 1: ICEF1 (Q8WWN9)
Interactor protein for cytohesin exchange factors 1 (Phosphoinositide-binding protein PIP3-E)
Gene: IPCEF1

Interactor 2: CYH2 (Q99418)
Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)
Gene: CYTH2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.936

The method score is based on:

Property Details
Experiments 12920129, 28514442, 32296183, 33961781, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, pull down, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PH, PH~Sec7
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 437
Hs

1 400
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024