HitPredict

Interactor 1: PHIP (Q8WWQ0)
PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
Gene: PHIP

Interactor 2: HDA11 (Q96DB2)
Histone deacetylase 11 (HD11) (EC 3.5.1.98)
Gene: HDAC11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23752268
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1821 Hs			1 347
+	Mm
		101519 F8VQ93_MOUSE (1-1821): 0: 1509: 94.89		HDAC4_MOUSE (1-341): 6.57e-129: 396: 21.60
+	Mm
		1157772 PHIP_MOUSE (1-1821): 0: 1506: 94.78		HDAC4_MOUSE (1-341): 6.57e-129: 396: 21.60
+	Hs
		1262831 PHIP_HUMAN (1-1821): 0: 1502: 100.00		HDAC6_HUMAN (18-346): 8.68e-95: 307: 21.31
+	Hs
		903202 WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		1038686 TBL1R_HUMAN (299-580): 2.26e-57: 210: 13.71		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		880817 TBL1R_HUMAN (299-580): 2.26e-57: 210: 13.71		HDAC4_HUMAN (1-341): 1.28e-127: 393: 20.53
+	Hs
		903404 WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		177249 WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Dm
		1212080 EBI_DROME (10-302): 2.44e-59: 220: 13.25		Q8I9J6_DROME (2-340): 7.25e-121: 378: 21.15
+	Hs
		1270358 FBXW7_HUMAN (294-657): 3.51e-56: 211: 17.33		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Dm
		1182201 EBI_DROME (10-302): 2.44e-59: 220: 13.25		Q7KTS4_DROME (14-334): 2.07e-124: 366: 21.24
+	Hs
		1270423 TBL1R_HUMAN (299-580): 2.26e-57: 210: 13.71		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		177377 TBL1R_HUMAN (299-580): 2.26e-57: 210: 13.71		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Hs
		1260173 FBXW7_HUMAN (294-657): 3.51e-56: 211: 17.33		HDAC7_HUMAN (13-344): 1.91e-121: 373: 19.89
+	Hs
		1260185 TBL1R_HUMAN (299-580): 2.26e-57: 210: 13.71		HDAC7_HUMAN (13-344): 1.91e-121: 373: 19.89
+	Dm
		1279322 EBI_DROME (10-302): 2.44e-59: 220: 13.25		Q9VNC2_DROME (14-334): 3.91e-123: 362: 21.24
+	Hs
		1270370 SNR40_HUMAN (355-666): 5.05e-55: 198: 13.23		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Mm
		1157725 PB1_MOUSE (1114-1652): 3.44e-41: 169: 15.70		HDAC4_MOUSE (1-341): 6.57e-129: 396: 21.60
+	Mm
		101536 F8VQD1_MOUSE (1114-1647): 4.33e-40: 165: 15.09		HDAC4_MOUSE (1-341): 6.57e-129: 396: 21.60
+	Hs
		1260194 BRWD1_HUMAN (1-298): 6.14e-41: 168: 15.76		HDAC7_HUMAN (13-344): 1.91e-121: 373: 19.89