HitPredict

Interactor 1: PHIP (Q8WWQ0)
PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
Gene: PHIP

Interactor 2: SIR7 (Q9NRC8)
NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Gene: SIRT7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22586326
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1821 Hs			1 400
+	Hs
		1016333 TBL3_HUMAN (7-495): 2.68e-90: 315: 14.31		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1199203 PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1016300 TBL3_HUMAN (7-495): 2.68e-90: 315: 14.31		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		1344499 NLE1_HUMAN (1-79): 1.4e-13: 77.6: 12.66		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1236482 TBL1R_HUMAN (299-580): 2.26e-57: 210: 13.71		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		1199159 PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		1281302 FBXW7_HUMAN (294-657): 3.51e-56: 211: 17.33		SIR1_HUMAN (78-380): 5.06e-78: 257: 19.94