HitPredict

Interactor 1: RASF5 (Q8WWW0)
Ras association domain-containing protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL)
Gene: RASSF5

Interactor 2: SAV1 (Q9H4B6)
Protein salvador homolog 1 (45 kDa WW domain protein) (hWW45)
Gene: SAV1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	24981860, 20920251
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 383
+	Hs
		1330813 RASF1_HUMAN (87-410): 5.15e-145: 418: 45.10		SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00
+	Hs
		1262928 RASF5_HUMAN (1-418): 0: 574: 100.00		ITCH_HUMAN (41-315): 8.61e-36: 141: 19.36
+	Hs
		1336090 RASF1_HUMAN (87-410): 5.15e-145: 418: 45.10		SMUF1_HUMAN (147-381): 2.43e-59: 206: 18.32
+	Hs
		1203195 RASF3_HUMAN (180-413): 3.65e-83: 256: 44.87		SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00
+	Hs
		1294869 RASF1_HUMAN (87-410): 5.15e-145: 418: 45.10		ITCH_HUMAN (41-315): 8.61e-36: 141: 19.36
+	Hs
		1172536 RASF6_HUMAN (252-411): 7.24e-58: 195: 25.29		SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00
+	Hs
		841565 RASF2_HUMAN (223-418): 2.59e-56: 190: 26.96		SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00
+	Dm
		1363056 Q9VCQ7_DROME (76-414): 1.25e-110: 344: 19.68		SAV_DROME (81-373): 5.46e-33: 131: 32.12
+	Hs
		1329566 RASF4_HUMAN (177-415): 8.43e-39: 143: 24.19		SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00