HitPredict

Interactor 1: RASF5 (Q8WWW0)
Ras association domain-containing protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL)
Gene: RASSF5

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.700

Property	Details
Experiments	25217643, 25416956, 26871637, 31515488
Identification Methods	affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 605
+	Hs
		3292 RASF5_HUMAN (1-418): 0: 574: 100.00		A0A0S2Z507_HUMAN (1-605): 0: 534: 95.13
+	Hs
		1345290 RASF1_HUMAN (87-410): 5.15e-145: 418: 45.10		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1345288 RASF1_HUMAN (87-410): 5.15e-145: 418: 45.10		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1203204 RASF3_HUMAN (180-413): 3.65e-83: 256: 44.87		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1203203 RASF3_HUMAN (180-413): 3.65e-83: 256: 44.87		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69