HitPredict

Interactor 1: ASB5 (Q8WWX0)
Ankyrin repeat and SOCS box protein 5 (ASB-5)
Gene: ASB5

Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24337577
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cullin~SOCS_box
Common GO terms	GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 329 Hs			1 780
+	Hs
		1274012 ASB9_HUMAN (69-328): 1.24e-91: 276: 52.69		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1263828 ASB11_HUMAN (6-329): 5.61e-86: 263: 53.85		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		556700 ANK1_HUMAN (1-286): 2.25e-79: 265: 26.37		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1021397 ANK3_HUMAN (1-252): 7.29e-67: 229: 23.26		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1042562 EHMT1_HUMAN (39-292): 7.59e-66: 226: 26.07		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1021398 ANK3_HUMAN (1-252): 7.29e-67: 229: 23.26		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		883509 RIPK4_HUMAN (2-176): 2.35e-39: 149: 18.99		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		1041199 Q9H4D1_HUMAN (2-176): 9.18e-39: 147: 18.99		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		862036 DAPK1_HUMAN (129-328): 1.34e-36: 141: 17.65		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1274048 ASB7_HUMAN (155-328): 2.01e-23: 99: 22.10		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1264015 ASB13_HUMAN (4-142): 2.31e-21: 93.8: 22.54		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1264027 ASB12_HUMAN (72-329): 3.23e-20: 90.9: 28.78		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1274096 ASB1_HUMAN (68-326): 4.99e-20: 90.9: 28.83		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		166925 ANR28_HUMAN (168-327): 1.91e-31: 126: 23.60		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1274095 ASB3_HUMAN (41-260): 1.59e-15: 79: 30.57		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1042160 ASB13_HUMAN (4-142): 2.31e-21: 93.8: 22.54		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1042298 EHMT2_HUMAN (205-327): 5.37e-15: 78: 23.02		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1043086 MIB1_HUMAN (155-326): 8.98e-18: 86.1: 18.86		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		1043332 ASB3_HUMAN (41-260): 1.59e-15: 79: 30.57		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		1043444 MIB1_HUMAN (155-326): 8.98e-18: 86.1: 18.86		CUL4B_HUMAN (16-780): 0: 736: 25.39