HitPredict

Interactor 1: EDAD (Q8WWZ3)
Ectodysplasin-A receptor-associated adapter protein (EDAR-associated death domain protein) (Protein crinkled homolog)
Gene: EDARADD

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.681

Property	Details
Experiments	25416956, 22924441, 16251197
Identification Methods	two hybrid, affinity chromatography technology, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 522
+	Hs
		1020834 EDAD_HUMAN (1-215): 1.48e-167: 461: 100.00		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85