HitPredict

Interactor 1: NELFB (Q8WX92)
Negative elongation factor B (NELF-B) (Cofactor of BRCA1)
Gene: NELFB

Interactor 2: NELFA (Q9H3P2)
Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein)
Gene: NELFA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.737

Property	Details
Experiments	24981860, 26496610, 28514442, 12612062, 33961781, 20305087
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032021 - NELF complex GO:0034244 - negative regulation of transcription elongation by RNA polymerase II
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 580 Hs			1 528
+	Dm
		1197390 NELFB_DROME (4-579): 0: 903: 52.21		NELFA_DROME (1-491): 3.1e-39: 154: 30.94