HitPredict

Interactor 1: RUFY2 (Q8WXA3)
RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related)
Gene: RUFY2

Interactor 2: RUFY1 (Q96T51)
RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (La-binding protein 1) (Rab4-interacting protein) (Zinc finger FYVE domain-containing protein 12)
Gene: RUFY1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 28514442, 33961781, 26496610, 36282215
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FYVE~FYVE, RUN~RUN
Common GO terms GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0017124 - SH3 domain binding
GO:0030100 - regulation of endocytosis
GO:0046872 - metal ion binding
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 606
Hs

1 708
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024