HitPredict

Interactor 1: SREK1 (Q8WXA9)
Splicing regulatory glutamine/lysine-rich protein 1 (Serine/arginine-rich-splicing regulatory protein 86) (SRrp86) (Splicing factor, arginine/serine-rich 12) (Splicing regulatory protein 508) (SRrp508)
Gene: SREK1

Interactor 2: MK67I (Q9BYG3)
MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar phosphoprotein Nopp34) (Nucleolar protein interacting with the FHA domain of pKI-67) (hNIFK)
Gene: NIFK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 508 Hs			1 293
+	Hs
		1031403 SREK1_HUMAN (1-508): 1.81e-52: 187: 100.00		PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66
+	Hs
		516607 SREK1_HUMAN (1-508): 1.81e-52: 187: 100.00		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		1263316 SREK1_HUMAN (1-508): 1.81e-52: 187: 100.00		PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96
+	Dm
		1369905 Q9VL71_DROME (3-188): 3.87e-34: 136: 33.16		Q9VM49_DROME (27-169): 3.37e-12: 68.4: 17.01
+	Dm
		1250404 Q9VL71_DROME (3-188): 3.87e-34: 136: 33.16		PUF68_DROME (47-118): 3.97e-10: 62.1: 34.72
+	At
		983454 CID8_ARATH (20-152): 8.54e-16: 80.2: 28.36		PABP5_ARATH (40-251): 3.14e-26: 109: 13.62
+	At
		790118 CID12_ARATH (20-147): 3.84e-22: 99.4: 29.69		PABP2_ARATH (126-225): 1.93e-10: 63.2: 4.90
+	Dm
		1187389 Q7YZ99_DROME (221-506): 5.49e-16: 83.3: 18.15		PUF68_DROME (47-118): 3.97e-10: 62.1: 34.72
+	At
		790115 CID8_ARATH (20-152): 8.54e-16: 80.2: 28.36		PABP2_ARATH (126-225): 1.93e-10: 63.2: 4.90