HitPredict

Interactor 1: ATRIP (Q8WXE1)
ATR-interacting protein (ATM and Rad3-related-interacting protein)
Gene: ATRIP

Interactor 2: TOPB1 (Q92547)
DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1)
Gene: TOPBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.646

The method score is based on:

Property Details
Experiments 24990965, 30940728, 17616665
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 791
Hs

1 1522
+ Xl

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Last updated: 15 Jul 2024