Interactor 1: STON2 (Q8WXE9)
Stonin-2 (Stoned B)
Gene: STON2

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 11454741, 26186194, 28514442, 33961781, 19380743
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adap_comp_sub~Adap_comp_sub, Adap_comp_sub~Clat_adaptor_s
Common GO terms GO:0005829 - cytosol
GO:0030122 - AP-2 adaptor complex
GO:0035615 - clathrin adaptor activity
GO:0048488 - synaptic vesicle endocytosis
GO:0072583 - clathrin-dependent endocytosis
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 905
Hs

1 435
+ Rn
+ Hs
+ Hs
+ Dm
+ At
+ Sc
+ Sc
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024