HitPredict

Interactor 1: STON2 (Q8WXE9)
Stonin-2 (Stoned B)
Gene: STON2

Interactor 2: EP15R (Q9UBC2)
Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)
Gene: EPS15L1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.854

Property	Details
Experiments	11381094, 33961781, 18200045
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, isothermal titration calorimetry
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	EF-hand_4~Stonin2_N
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 905 Hs			1 864
+	Hs
		787954 STON2_HUMAN (1-905): 0: 1331: 100.00		EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20
+	Hs
		1078883 STON2_HUMAN (1-905): 0: 1331: 100.00		ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31
+	Hs
		1263435 STON2_HUMAN (1-905): 0: 1331: 100.00		EHD1_HUMAN (198-366): 4.94e-14: 77.8: 25.44
+	Rn
		64454 Q7TNJ9_RAT (367-881): 3.88e-169: 511: 40.96		A7BFV9_RAT (1-862): 1.06e-104: 346: 41.35
+	Hs
		1287519 AP2M1_HUMAN (472-871): 2.4e-126: 389: 18.53		EP15R_HUMAN (1-864): 1.18e-150: 466: 100.00
+	Hs
		787959 AP2M1_HUMAN (472-871): 2.4e-126: 389: 18.53		EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20
+	Hs
		1349325 AP1M2_HUMAN (427-871): 1.11e-148: 447: 19.91		EHD2_HUMAN (262-365): 6.81e-22: 102: 34.62
+	Hs
		1078888 AP2M1_HUMAN (472-871): 2.4e-126: 389: 18.53		ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31
+	Ce
		725368 AP2M_CAEEL (473-871): 1.04e-120: 375: 18.78		Q9U2T9_CAEEL (119-652): 4.86e-35: 146: 17.92
+	Hs
		1287515 AP2M1_HUMAN (472-871): 2.4e-126: 389: 18.53		ITSN2_HUMAN (2-531): 1.52e-24: 112: 11.86
+	Hs
		1287516 AP2M1_HUMAN (472-871): 2.4e-126: 389: 18.53		EHD2_HUMAN (262-365): 6.81e-22: 102: 34.62
+	Dm
		91158 STNB_DROME (372-876): 1.31e-127: 416: 29.72		E3CTP7_DROME (504-831): 1.9e-12: 73.2: 8.54
+	Hs
		1244783 AP2M1_HUMAN (472-871): 2.4e-126: 389: 18.53		REPS2_HUMAN (14-99): 3.33e-12: 72.3: 24.42