HitPredict

Interactor 1: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Interactor 2: DDX1 (Q92499)
ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB)
Gene: DDX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0045087 - innate immune response
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 523 Hs			1 740
+	Hs
		134137 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		DDX3X_HUMAN (1-380): 2.46e-40: 159: 13.47
+	Hs
		1263493 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		DDX17_HUMAN (1-381): 4.07e-36: 147: 12.21
+	Hs
		571527 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		DDX5_HUMAN (1-381): 2.38e-34: 141: 11.96
+	Hs
		133858 PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16		DDX3X_HUMAN (1-380): 2.46e-40: 159: 13.47
+	Hs
		613538 SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14		DDX17_HUMAN (1-381): 4.07e-36: 147: 12.21
+	Hs
		757698 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		IF4A3_HUMAN (3-72): 3.92e-11: 67.8: 30.00
+	Sc
		376580 PABP_YEAST (4-373): 1.42e-48: 178: 14.85		DED1_YEAST (1-380): 8.1e-36: 145: 13.97
+	Hs
		516391 PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16		IF4A3_HUMAN (3-72): 3.92e-11: 67.8: 30.00
+	Hs
		134018 PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83		DDX3X_HUMAN (1-380): 2.46e-40: 159: 13.47
+	Hs
		1077436 ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11		DDX17_HUMAN (1-381): 4.07e-36: 147: 12.21
+	Hs
		571469 ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11		DDX5_HUMAN (1-381): 2.38e-34: 141: 11.96
+	Hs
		1271643 RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14		DDX17_HUMAN (1-381): 4.07e-36: 147: 12.21
+	Hs
		571581 RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14		DDX5_HUMAN (1-381): 2.38e-34: 141: 11.96