HitPredict

Interactor 1: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0045087 - innate immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 523 Hs			1 783
+	Hs
		516711 PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1204680 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		DDX42_HUMAN (2-757): 4.87e-137: 430: 20.41
+	Hs
		1263493 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		134137 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571527 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		133858 PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		1069733 NONO_HUMAN (50-523): 4.22e-68: 228: 57.60		DDX42_HUMAN (2-757): 4.87e-137: 430: 20.41
+	Hs
		613512 SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14		DDX42_HUMAN (2-757): 4.87e-137: 430: 20.41
+	Hs
		613538 SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		1077513 ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1314627 RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		134018 PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		1077436 ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		571469 ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		1308743 RBM4B_HUMAN (83-190): 4.07e-09: 60.5: 33.04		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1271643 RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		571581 RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		757698 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		516391 PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Sc
		376580 PABP_YEAST (4-373): 1.42e-48: 178: 14.85		DED1_YEAST (196-541): 2.98e-56: 205: 37.98