HitPredict

Interactor 1: MADD (Q8WXG6)
MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (Rab3GEP)
Gene: MADD

Interactor 2: SYT3 (Q9BQG1)
Synaptotagmin-3 (Synaptotagmin III) (SytIII)
Gene: SYT3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1647 Hs			1 590
+	Hs
		1197916 MADD_HUMAN (1-1647): 0: 2403: 100.00		SYT9_HUMAN (7-571): 6.65e-128: 386: 46.21
+	Hs
		1134920 MADD_HUMAN (1-1647): 0: 2403: 100.00		SYT6_HUMAN (10-583): 9.87e-115: 353: 43.95
+	Hs
		1217015 MADD_HUMAN (1-1647): 0: 2403: 100.00		SYT12_HUMAN (184-569): 6.62e-78: 254: 26.17
+	Hs
		1238327 MADD_HUMAN (1-1647): 0: 2403: 100.00		SYT2_HUMAN (261-434): 1.08e-26: 114: 28.50