HitPredict

Interactor 1: P66B (Q8WXI9)
Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68)
Gene: GATAD2B

Interactor 2: SALL1 (Q9NSC2)
Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1)
Gene: SALL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 34795231
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 593 Hs			1 1324
+	Hs
		1205821 P66A_HUMAN (4-590): 0: 551: 38.75		SALL1_HUMAN (1-1324): 0: 631: 85.58
+	Hs
		1263992 P66B_HUMAN (1-593): 0: 801: 100.00		SALL4_HUMAN (1116-1215): 6.58e-15: 82.3: 26.92
+	Mm
		1207422 P66B_MOUSE (1-593): 0: 789: 98.32		SALL4_MOUSE (1116-1215): 5.25e-14: 79.2: 26.92
+	Mm
		50775 A1L3S7_MOUSE (1-593): 0: 762: 95.79		SALL4_MOUSE (1116-1215): 5.25e-14: 79.2: 26.92
+	Hs
		1205833 P66A_HUMAN (4-590): 0: 551: 38.75		SALL4_HUMAN (1116-1215): 6.58e-15: 82.3: 26.92
+	Mm
		1207418 P66A_MOUSE (4-590): 0: 540: 37.24		SALL4_MOUSE (1116-1215): 5.25e-14: 79.2: 26.92