HitPredict

Interactor 1: ASB13 (Q8WXK3)
Ankyrin repeat and SOCS box protein 13 (ASB-13)
Gene: ASB13

Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.930

Property	Details
Experiments	28514442, 31253590, 33961781, 21145461, 24337577
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cullin~SOCS_box
Common GO terms	GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 278 Hs			1 780
+	Hs
		1274012 ASB9_HUMAN (18-277): 3.47e-71: 222: 41.92		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1042160 ASB13_HUMAN (4-278): 8.73e-74: 228: 100.00		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1042298 EHMT2_HUMAN (7-268): 1.42e-64: 220: 27.55		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		556700 ANK1_HUMAN (54-275): 3.28e-44: 161: 22.13		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1021397 ANK3_HUMAN (122-278): 1.41e-42: 157: 20.89		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1274043 TNKS2_HUMAN (11-133): 1.41e-28: 116: 24.80		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1021398 ANK3_HUMAN (122-278): 1.41e-42: 157: 20.89		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		1262947 ASB5_HUMAN (1-176): 8.01e-27: 108: 27.84		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1274048 ASB7_HUMAN (104-258): 5.83e-22: 94.9: 18.65		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1263828 ASB11_HUMAN (91-276): 1.97e-21: 93.4: 19.79		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1264027 ASB12_HUMAN (54-277): 3.15e-21: 92.8: 31.75		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1274095 ASB3_HUMAN (51-218): 1.67e-13: 72: 27.84		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		862036 DAPK1_HUMAN (1-113): 5.96e-24: 103: 23.01		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1042562 EHMT1_HUMAN (13-130): 1.05e-22: 99.5: 27.73		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		166925 ANR28_HUMAN (7-127): 6.58e-13: 70.5: 23.20		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1042054 ANR52_HUMAN (20-216): 2.1e-10: 63.2: 27.81		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		883509 RIPK4_HUMAN (154-278): 1.96e-12: 69: 16.67		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		1041199 Q9H4D1_HUMAN (154-278): 2.94e-12: 68.6: 16.67		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		1043332 ASB3_HUMAN (51-218): 1.67e-13: 72: 27.84		CUL4A_HUMAN (16-780): 0: 744: 24.48